Comparison of magnesium preparations. Which magnesium to choose? Which magnesium is better and easier to absorb by the human body. Instructions for use and dosage

Magnesium is an indispensable macronutrient, it takes part in vital processes in the body. With a deficiency of magnesium, various disorders occur, so the doctor prescribes drugs with this substance.

Magnesium and indications for admission

Up to 50% of the population is deficient in magnesium. The body suffers from this, complications gradually develop. Magnesium is responsible for the normal excitability of the nervous system, reduces inflammation and allergies, regulates heart function and blood clotting. Also, the element helps the work of the prostate, intestines, bladder, participates in the construction of bones. The element is especially important for pregnant women and children.

Without magnesium, normal metabolism at all levels is impossible.

To make up for the deficiency of the substance, it is required to take medications. It is important that Mg is present in them in an easily digestible form. Some forms (for example, magnesium oxide) are not useful for those suffering from kidney diseases, they cause the deposition of salts in the kidneys. Mg is well absorbed in the form of:

There must be indications for taking the tablets. It is recommended to treat with convulsions, irritability. Means are indicated for arrhythmias, muscle pain, fatigue, hair loss. For children, drugs are recommended in the complex treatment of vascular problems, spinal instability, and connective tissue dysplasia. In adults, drugs that contain magnesium complement the therapy of hypertension, tachycardia.

Magne B6 and Magnelis

These drug names are considered the most popular in the list of doctors' prescriptions for magnesium therapy. Magne B6 additionally contains vitamin B6, due to which the element is well absorbed and has a more pronounced effect on the nervous system. In pharmacies, the following types of medicines are sold:

The dosage of the medicine is selected only by the doctor. Usually, children are prescribed 0.5-3 ampoules per day, or 2-6 tablets. The adult dose can be up to 8 tablets per day. The remedy is recommended for stress, insomnia, it is prescribed during pregnancy and while taking diuretics.

The exact structural analogue of Magne B6, but these tablets are cheaper, although no less effective. For 50 tablets you need to pay 360 rubles, and they are taken in the same mode. Against the background of therapy with these drugs, abdominal pain, nausea, dry mouth, and constipation often occur.

Magnerot and Magnesium Diasporal

One of the best magnesium preparations is Magnerot. In its composition -. A feature of the product is the presence of orotic acid, which is involved in metabolism, promotes the growth of healthy cells. The drug is well absorbed, because thanks to orotic acid, Mg is fixed in the cells and fully manifests its effect.

The element is a natural calcium antagonist, which must be taken into account during therapy.

During treatment, unstable stools are most often noted (due to the high concentration of the element). The remedy is especially indicated for hypertension, heart failure, arrhythmia, atherosclerosis. Children under 18 years of age are not prescribed. Adults drink 3-6 tablets / day.

Magnesium Diasportal is considered quite expensive, but highly effective (720 rubles for 20 sachets). The element is present in the form of citrate, which is absorbed most fully. Adults, children from 12 years of age should drink a sachet / day to make up for the deficiency of the element. Due to the presence of sucrose, the drug is drunk with caution in diabetes mellitus.

Panangin and Asparkam

The most inexpensive pills that include Mg (price - from 40 rubles). The difference between Asparkam and only in price, since the latter is produced by a foreign company (price 170 rubles). The composition additionally contains potassium, and both substances are in the form of aspartate. In the complex, the elements have the following actions:

Taking drugs should be carried out carefully, they can cause hypermagnesemia, hyperkalemia. Against the background of such problems, convulsions, heart blockade, respiratory depression occur. During pregnancy, lactation, drugs are prescribed under the supervision of a physician. Medicines are allowed for children from birth, but the dose is selected individually.

Magnistad and Magnesol

Among the list of inexpensive and effective magnesium preparations, Magnistad (360 rubles / 50 tablets) should be indicated. As part of Mg in the form of lactate, as well as pyridoxine. Therapeutic doses of substances can eliminate the deficiency that occurs due to poor nutrition, alcoholism, dehydration.

Pyridoxine significantly improves the absorption of Mg in the intestine.

The specified form of the element is excreted by the kidneys, therefore, people with chronic renal failure are contraindicated. Taking on an empty stomach most often causes diarrhea, so drink the drug with meals. Children from 6 years old, adults are recommended 6-8 tablets / day.

Magnesium is a universal regulator of physiological and biochemical processes in the body (functioning of the nervous tissue and conduction system of the heart); the body's supply of magnesium contributes to better tolerance of stressful situations and the suppression of depression. Magnesium is needed by the body to break down fat. The function of magnesium is to promote the fastest activation of metabolism.
Important for the metabolism of calcium and vitamin C, as well as phosphorus, sodium and potassium. It is measured in milligrams (mg). Important for the efficient functioning of nerves and muscles. Important for converting blood sugar into energy. Known as an anti-stress mineral.

magnesium deficiency in the body is inherent in the population of the whole world. The most common nutritional deficiency of magnesium, the causes of which may be:
- insufficient content of it in food, water or general malnutrition;
- excess calcium, protein or fat in food that is complete in other respects, which significantly reduces its intake into the body (associated with the formation of non-absorbable magnesium complexes);
- chronic alcoholism, especially with withdrawal syndrome;
- physical stress;
- hypodynamia;
- stress;
- pregnancy and lactation;
- hormonal contraception;
- chronic excess of mineralocorticoids;
- febrile conditions occurring with high fever, vomiting and intestinal upset.

Local or general deficiency magnesium can occur in various diseases of the internal organs:
- kidneys, in particular with a diabetic kidney;
- in the presence of intestinal fistulas due to impaired absorption of magnesium in the intestine;
- with diabetes mellitus with high blood sugar levels;
- arterial hypertension;
- myocardial infarction;
- circulatory failure, especially congestive;
- overdose of cardiac glycosides;
- increased function of the thyroid gland;
- increased function of the parathyroid glands;
- increased production of the adrenal hormone - aldosterone;
- cirrhosis of the liver;
- may be related to premenstrual syndrome;
- long-term use of diuretic drugs in high doses;
- long-term treatment with glucocorticosteroids (prednisolone, etc.) or cytostatic drugs.

to magnesium deficiency long-term use of antibiotics (for example, gentamicin, carbenicillin, etc.), alcohol abuse, malabsorption in the small intestine can also lead.

Excess magnesium.
Large doses of magnesium have almost no effect on the state of the body.

Sources of magnesium: unprocessed foods such as whole grains, lentils, peanuts, tree nuts. Enough magnesium is present in bananas, apricots, avocados, apples, red peppers, grapefruit, lemons, as well as cheese, sesame seeds, wheat, yeast, dairy products, fish and meat.

Best Natural Sources: Figs, lemons, grapefruits, yellow grains, almonds, nuts, seeds, dark green vegetables, apples Dolomite, which contains magnesium and calcium in an ideal proportion (magnesium is half that of calcium), is an excellent magnesium supplement .

Assimilation.
Assimilation decreases with the use of large amounts of fats, proteins, vitamin D. Its absorption is affected by oxalic acid contained in almonds, beets, cocoa, rhubarb, and tea.
Stress leads to a decrease in the amount of magnesium in the body.
The body's need for magnesium increases with alcohol, with diarrhea, with a single large intake of vitamin D, zinc, and phosphorus.

Magnesium intake.
Magnesium supplements should not be taken after meals as this mineral neutralizes stomach acid.

Interactions.
Calcium can reduce the absorption of magnesium, since these two metals share a common transport system in the intestines. The ratio of calcium to magnesium in the diet should be 2:1.
A high fat diet can reduce magnesium absorption because fatty acids and magnesium form soap-like salts that are not absorbed in the gastrointestinal tract.
High fiber foods can contribute to the loss of certain minerals, including magnesium.
Supplementing with folic acid may increase the need for magnesium due to an increase in the activity of enzymes that require magnesium to function properly.
Iron can reduce the absorption of magnesium from the gut.
Calciferol (vitamin D) stimulates to some extent the absorption of magnesium in the intestine; however, since the stimulatory effect is more pronounced on calcium, additional intake of this vitamin can create a relative deficiency of magnesium.
Vitamin E deficiency can lower tissue magnesium levels.
Alcohol, potassium, and caffeine all increase magnesium loss through the kidneys.
Consuming large amounts of sugar increases the need for magnesium.
A high-protein diet increases the need for magnesium, especially in the rapid construction of new body tissues - in growing children, exercising athletes, pregnant women and nursing mothers.
The B vitamins require magnesium to function properly.
People taking digitalis may develop abnormal heart rhythms if they have a magnesium deficiency.
Certain diuretics cause an increase in magnesium loss through the kidneys.

Advantages.
Promotes bone growth.
Contributes to the normal function of nerves and muscles, including the regulation of heart rate.
Serves as a conductor of nerve impulses.
In large doses, it acts as a laxative.
In small doses, it acts as an acid neutralizer.
Strengthens tooth enamel.

Possible additional benefits:
Reduces the effects of lead poisoning.
Reduces kidney stones.
Can be used in the treatment of heart disease.

Additional intake may be required:
- people who consume low-calorie or insufficiently nutrient-dense food, as well as those who experience an increased need for nutrients;
- those who use alcohol and drugs;
- people suffering from severe chronic diseases;
- have recently undergone surgery.

Also, the need for magnesium may increase with vomiting and diarrhea.

Caveats.

If you suffer from kidney disease, please avoid magnesium supplementation without the direct and close supervision of your physician or nephrologist.

Magnesium supplements should not be taken after meals, as this neutralizes stomach acid.

Over the age of 55, the likelihood of a backlash and side effects increases.

Do not take magnesium during pregnancy. During the feeding period - only as prescribed by your doctor.

Magnesium should be an integral part of any dietary program to improve sleep. It not only contributes to a more complete rest, but also counteracts bruxism - the involuntary grinding of teeth during sleep.
The range of other therapeutic effects of magnesium is very wide - it helps with chemical hypersensitivity, bacterial and viral infections, leg cramps, kidney stones and intermittent claudication - a violation of the blood supply to the legs, which causes pain with muscle tension.

Magnesium: One Cure for Many Diseases

Introduction, or why this article was written?

In 70% of the "inhabitants" of the cardioreanimation departments, a reduced level of magnesium in the blood is noted, and in the case of Acute Coronary Syndrome (diagnosis of the Ambulance for suspected heart attack) - in 90%. I think this explains my interest in magnesium deficiency.

When I studied the state of the issue on the Internet, 2 groups of articles on this topic became clearly visible. The first group is the serious work of researchers, written in complex terminology and incomprehensible to ordinary people without a medical education. The second is very understandable (like “drink magnesium - and a miracle will happen!”), But not very literate texts with a substitution of concepts and obvious commercial background.

I have made an attempt to write an article without serious errors and understandable for a wide range of patients. It turned out or not - to judge you, the reader. If you have any questions, wishes or comments, write, I will be happy to answer. Those who are interested in the topic, especially the evidence-based part of it, can read articles about magnesium for doctors on my website.

The role of magnesium in biology and medicine

Magnesium is one of the most "demanded" metals in wildlife. The center of the chlorophyll molecule (the green pigment of plants) is a magnesium atom. Chlorophyll "feeds" plants (grasses, trees, algae), which are eaten by herbivores, which in turn are eaten by predators. It turns out that magnesium ultimately feeds almost all wildlife. The magnesium atom has special properties due to which in the human body it is "embedded" in at least 300 enzymes that perform a huge number of "useful" functions.

The doctor (under the first diploma) Alexander Rosenbaum wrote in one of his songs: "There is anxiety on the face, there is magnesia in the syringe ... This is not for entertainment: there is no more effective treatment than its layered introduction ..."

Several decades have passed since the writing of these lines, and now it turned out that the jokey words of the poet-doctor turned out to be prophetic. In foreign countries, serious studies are being carried out on the role of magnesium on thousands of patients, governments (for example, Finland) are adopting magnesium deficiency prevention programs, the implementation of which gives a very serious decrease in the incidence (for 15 years of the program, the number of heart attacks in Finland has halved); Pharmaceutical companies are producing more and more different drugs containing this metal. Unfortunately, in the national guidelines for cardiology in our country, the use of magnesium is stipulated in only a few cases.

What conditions are associated with magnesium deficiency?

In medicine, there are situations when drugs created to treat a disease do not work. Or the reasons for the patient's condition are not very clear. At present, it has been scientifically proven that a very wide range of pathological conditions are caused precisely by magnesium deficiency in the body. I'll try to draw this circle:

1. Cardiology: high blood pressure, rapid or irregular heartbeat, high cholesterol and atherosclerosis (and, as a result, coronary heart disease with its formidable complication - a heart attack), a tendency to thrombosis, pain in the heart (cardialgia), mitral valve prolapse.

2. Psychoneurology: increased irritability, poor sleep, deterioration of mental abilities, depression, fatigue, vegetovascular dystonia (including with panic attacks and hyperventilation syndrome), muscle cramps and spasms (including nocturnal cramps of the calf muscles in women), risk of stroke with atherosclerosis of the vessels supplying the brain.

3. Pulmonology: bronchospasm (expiratory difficulty).

4. Gastroenterology: constipation or diarrhea, nausea, abdominal pain due to impaired gastrointestinal motility.

5. Urology: oxalate kidney stones or a tendency to stone formation.

6. Gynecology and obstetrics: premenstrual syndrome, miscarriage, increased pressure during pregnancy.

7. Endocrinology: hyperaldosteronism (fluid retention in the body).

8. Rheumatology, cosmetology: connective tissue diseases and skin aging as problems of collagen metabolism.

9. Oncology (although the information is still scarce and poorly verified): - Magnesium deficiency leads to an increase in the number of cancers.

10. Narcology: a very significant part of the origin of the "hangover syndrome" is due to the fact that alcohol expels magnesium from the body. Hence the use of magnesium preparations for the prevention and treatment of withdrawal symptoms.

Accordingly, all these conditions are corrected (understandably, to varying degrees and for different times) by saturating the body with magnesium.

The need for magnesium increases significantly with physical and emotional stress, alcohol abuse, pregnancy and lactation, chronic fatigue syndrome, eating certain foods (coffee), and taking medications.

Is magnesium deficiency determined by a blood test?

99% of magnesium in the human body is located inside the cells, so the content of the metal in the blood plasma reflects the state of the remaining one percent. The blood test in this case is much less accurate than your health. Here is a quote from the official website of the Invitro laboratory: "The level of magnesium in the serum can remain within normal limits even with a decrease in the total amount of magnesium in the body by 80%." More reliable is the determination of magnesium in erythrocytes, as well as in hair and nails.

Accordingly, if the blood test determines the content of magnesium below the norm, then its real deficiency in the body is huge.

How does the body get the right amount of magnesium?

According to the literature, the daily requirement for magnesium is 350 mg for women and 450 mg for men. Tables of magnesium content in foods are widely available on the Internet. The only problem is that far from all the magnesium contained in food is perceived by the body, and, according to the general opinion of doctors dealing with this issue, it is almost impossible to “eat” a normal amount of magnesium. Accordingly, it is necessary to provide the body with well-absorbed magnesium in adequate quantities.

Can magnesium poison you?

It is possible if a patient with severe kidney disease, who is on hemodialysis, will receive intravenous extra magnesium. In other cases, excess magnesium, when taken INSIDE, will be excreted by the intestines (through varying degrees of loosening of the stool). Specialists working in the field of stopping drinking binges, according to the standard scheme, administer to patients intravenously up to a gram of magnesium, and all the excess is excreted by the kidneys during the day. So our attempts to poison the body with a maximum of five hundred milligrams INSIDE will not be successful in any way.

What magnesium preparations are available on the Russian market?

Let's see what is sold in pharmacies. I do not consider network marketing products, as well as preparations of especially “shy” (or boorish?) Russian manufacturers that do not print the amount of magnesium in the instructions, for example, “Motherwort Forte”, “Sea Calcium” or “Magnesium Calcide” (manufacturers believe that You do not need to know “how much to hang in grams?”, And this shows great “respect” for you). Products sold in less than 10 out of 780 pharmacies in Moscow were also not considered. In fairness, I note that I am not on the salary of any of the pharmaceutical companies, so I can have my own subjective opinion (which may differ from the opinion of the reader - you can choose at your discretion).

The study was conducted based on the materials of the sites www.rlsnet.ru (the official register of medicines in Russia) and www.aptekamos.ru (the best pharmacy search engine in Moscow). If a dear reader sends me the name of other magnesium-containing drugs, I will be grateful.

In the "magnesium" column, the content of pure magnesium is estimated, without taking into account the weight of acid molecules (for example, the drug contains magnesium lactate 200 mg. The formula of magnesium lactate is MgC3H4O3. The atomic weight of magnesium is 24, the weight of lactate is 12x3 + 1x4 + 16x3 = 88, the total weight of the molecule is 112 , that is, magnesium itself makes up only less than a quarter of the weight of the drug).

Let's take a look at the resulting table. Let me remind you that the female daily requirement outside of pregnancy is 350 mg, the male - 450 mg per day.

Dear authors dealing with the issues of magnesium absorption, note that calcium significantly impairs the absorption of magnesium, so I reject all combinations of magnesium and calcium for myself. In addition, different salts have different degrees of digestibility: maximum - citrate, less - organic salts (lactate, pidolate, asparaginate), minimum - inorganic compounds (oxide, sulfate). It is also described that tablet preparations are absorbed by 60 percent at best.

Therefore, a little about the "liquid" drugs, which are absorbed much more fully. There are only three of them (without calcium): Magnesium Plus, Magne B6 in ampoules, Natural Calm. Now I describe my personal feelings and conclusions. Magnesium Plus - I have not personally tried it yet, four tablets (glasses of solution) can, in principle, get almost a full daily dose. Magne B6 I did not like the sweet caramel obsessive taste and the need to take again four ampoules a day. And one drug is taken in the form of a hot solution (in the morning and in the evening, half a cup), which accelerates and improves absorption.

As a result, Magnesium citrate preparations Natural Calm and MagneV6Forte are suitable for serious saturation, Doppelherz active preparations: Magnesium + B vitamins and Magnesium + Potassium are suitable for average saturation with minimal money. Everything else is somewhere in between.

Pharmstandard, represented by the Ufa Pharmaceutical Plant, claims a good drug Magnelis B6, containing about 100 mg of magnesium in the form of lactate, however, knowing the situation at Russian plants at the present time, I cannot be responsible for the reality of the statements. Time will show.

In the case of a single dose, magnesium preparations are best taken in the evening (sleep will improve).

How long to take magnesium supplements?

If you feel the effect of taking it and the drug does not cause side effects in you, you can (and should) take it FOR LIFE. Let me remind you that excess magnesium when taken orally is very quickly excreted by the body, and it is almost impossible to “eat” a normal concentration. So it's up to you to choose which pharmaceutical company to "pay tribute" to improve your condition.

There will be questions - write!

Magnesium protects us from atherosclerosis, stress, kidney stones and hemorrhoids. With a lack of magnesium, twitching of the muscles and eyelids, numbness of the extremities, bouts of despair, arrhythmia, and pain in the chest may appear. Rich sources of magnesium are cocoa, nuts, seeds, poppy seeds and soybeans.

Magnesium is absorbed mainly in the duodenum and slightly in the large intestine. But only organic magnesium compounds are well absorbed, for example, organic magnesium compounds in the composition of complexes with amino acids, organic acids (magnesium lactate, magnesium citrate), etc. Inorganic salts (magnesium sulfate) are absorbed very poorly.

It was found in the laboratory that as a result of even short-term stress, 80% of the daily dose of magnesium is consumed. And with chronic, prolonged stress, people feel “heaviness” in the heart, which simply signals problems with the cardiovascular system, that is, a sharp depletion of strategic reserves of trace elements. In addition to magnesium, potassium, zinc, chromium and other vital substances are consumed in extreme conditions. Therefore, in a problematic period, you need to take care of replenishing valuable substances in the body.

Magnesium citrate is a magnesium salt of citric acid C 6 H 6 O 7 Mg, a drug, a source of magnesium, one of the most important intracellular macronutrients in the body. The content of pure (elemental) Mg 2+ in the composition of magnesium citrate reaches approximately 11%.

According to the results of recent studies, magnesium citrate is found to be the most digestible magnesium-containing product. One of the most biologically appropriate sources of magnesium for transcutaneous (percutaneous) absorption is the mineral bischofite, which is widely used for medical rehabilitation, physiotherapy and spa treatment. The advantage of transcutaneous use is the high bioavailability of magnesium ions, which saturates local problem areas bypassing the excretory system.

Magnesium is a mineral that has beneficial effects on all important systems in your body. This chemical makes your bones strong, improves sleep, relieves pain, and improves heart health. That's why the lack of magnesium negatively affects your well-being. However, before you turn to taking vitamin complexes, you should learn about some important things.

Why take magnesium supplements?

Magnesium is found in our bones, muscles and cells. In addition, this mineral can be found in inanimate nature: in the earth's crust or sea water. According to the Academy of Nutrition and Dietetics, an adult needs between 300 and 400 mg of magnesium on a daily basis (depending on gender). And if you're not eating enough green leafy vegetables, whole grains, or beans, you should consider taking vitamins. This is due to the fact that a low level of magnesium in the body provokes an exacerbation of cardiovascular diseases, increases the risk of type 2 diabetes, osteoporosis and chronic migraines.

Signs of a magnesium deficiency

Unsure if you need extra vitamins? It is not necessary to take expensive blood tests. Lack of magnesium in the long term is expressed in loss of appetite, muscle fatigue, cramps, tingling in the limbs. Some people experience bouts of nausea, sometimes turning into vomiting, as well as heart rhythm disturbances.

What drug to choose?

There are several types of magnesium supplements, and choosing the right one makes a big difference. For example, magnesium citrate and magnesium chloride are better absorbed and provide fewer side effects than magnesium oxide. Magnesium aspartate and magnesium lactate are also easily absorbed. There is also a salt additive "Epsom Salt", which penetrates under the skin when taking a bath. However, scientists are still arguing about the effectiveness of this method. Some magnesium-based preparations may have a laxative effect, and some act as antacids.

Why is an overdose of magnesium dangerous?

Magnesium supplements in reasonable doses are completely safe. But if you take an increased prophylactic dose or get enough of the macronutrient in your diet, you may experience diarrhea. People who have kidney problems or diseases of the cardiovascular system should consult a doctor before going to a pharmacy. If you have no contraindications, then take the selected drug with food. This simple strategy reduces the risk of indigestion.

Add water

Do you want to increase bone strength or overcome depression? Magnesium will benefit your body more if you take it with plenty of water. Magnesium citrate powder can be mixed with spring or filtered water (either hot or cold) and sipped as a vitamin cocktail throughout the day. To make the healing macronutrient work even better, nutritionists recommend that their clients add a little sea salt, which contains a dozen valuable minerals, to a glass.

What vitamin supplements can be taken with magnesium?

Some vitamins and minerals work well with magnesium, and some interfere with absorption. For example, sea salt and vitamin B 6, included in the list of 13 essential vitamins to ensure the vital activity of the body, perfectly complement each other. But magnesium and calcium become antagonists, the same applies to the magnesium-zinc pair. Therefore, if you are considering multivitamin mineral complexes, we advise you to abandon this idea. In fact, multivitamins are useless, so manage your money more wisely.

Purchase calcium, magnesium, and zinc supplements separately. For best absorption, take them at two-hour intervals. Also be aware that magnesium can reduce the absorption of certain medications, such as diabetes medications, diuretics, and medications to treat osteoporosis. If you have at least one of these medical conditions, be sure to consult your doctor regarding the additional intake of vitamin supplements.

What time of day is best to take supplements?

Several scientific studies have found that magnesium is best taken in the evening, as it helps to loosen the muscles of the body and make it easier to fall asleep.

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